2017, Vol. 2, Issue 2
Vinca alkaloid- the second most used alkaloid for cancer treatment- A review
Author(s): Mohammad Abu Taher, Mohammad Abu Bin Nyeem, Md. Masum Billah and Md. Monir Ahammed
This review is aimed at conferring the efficacy of anticancer property of different phytochemicals from Nayantara (Catharanthus roseus). Cancer is one of public health burden in developed and developing country. Cancer chemo preventive agents, many of which are natural products, are capable of preventing or inhibiting the process of carcinogenesis. Herbal anticancer drug are obtained from Catharanthus roseus is wildly used because of their well defined mechanism of action as anticancer drug. The main alkaloids of Catharanthus roseus is vinca alkaloids which is important for being cancer fighters. There are four major vinca alkaloids in clinical use: vinblastine (VBL), vinorelbine (VRL), vincristine (VCR) and vindesine (VDS). Recently vinflunine is discovered as new anticancer agent of vinca alkaloids. In this review, an attempt has been made to summarize the pharmacological effect of the above plant against anticancer property in a precise way to help the scientist and learners to understand the basis medicinal value of the plant.
Pages: 723-727 | 542 Views 19 Downloads
How to cite this article:
Mohammad Abu Taher, Mohammad Abu Bin Nyeem, Md. Masum Billah, Md. Monir Ahammed. Vinca alkaloid- the second most used alkaloid for cancer treatment- A review. Int J Physiol Nutr Phys Educ 2017;2(2):723-727.