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International Journal of Physiology, Nutrition and Physical Education

Impact Factor (RJIF): 5.48

ISSN: 2456-0057

2018, Vol. 3, Issue 1
Neurological and mental disorders
Author(s): Mallikarjun C Pujari, Vijay kumar SD
Abstract:
Over the last decade and a half, reinforcement learning models have fostered an increasingly sophisticated understanding of the functions of dopamine and corticoid-basal ganglia-thalami-cortical (CBGTC) circuits. More recently, these models, and the insights that they afford, have started to be used to understand key aspects of several psychiatric and neurological disorders that involve disturbances of the dopaminergic system and CBGTC circuits. We review this approach and its existing and potential applications to Parkinson’s disease, Torte’s syndrome, attention-deficit/hyperactivity disorder, addiction, schizophrenia, and preclinical animal models used to screen novel antipsychotic drugs. The approach’s proven explanatory and predictive power bodes well for the continued growth of computational psychiatry and computational neurology.
Pages: 809-811  |  674 Views  32 Downloads
How to cite this article:
Mallikarjun C Pujari, Vijay kumar SD. Neurological and mental disorders. Int J Physiol Nutr Phys Educ 2018;3(1):809-811.
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