2018, Vol. 3, Issue 2
RNA interference: A comprehensive knowledge gain regarding gene knock-down from cell physiology
Author(s): Dr. Amitabha Kar
Over the past decade RNA interference (RNAi) has emerged as a natural mechanism for silencing gene expression. This ancient cellular antiviral response can be exploited to allow specific inhibition of the function of any chosen target gene. RNAi is proving to be an invaluable research tool, allowing much more rapid characterization of the function of known genes. More importantly, RNAi technology considerably bolsters functional genomics to aid in the identification of novel genes involved in disease processes.
This review briefly describes the molecular principles underlying the biology of RNAi phenomenon and discuss the main technical issues regarding optimization of RNAi experimental design.
Pages: 1079-1082 | 664 Views 34 Downloads
How to cite this article:
Dr. Amitabha Kar. RNA interference: A comprehensive knowledge gain regarding gene knock-down from cell physiology. Int J Physiol Nutr Phys Educ 2018;3(2):1079-1082.