This study aims to investigate the health and lifestyle of Indian youth residing in diverse cities. A total of 400 individuals, aged 16 to 28, representing a crucial phase of young adulthood, were surveyed using the "Student Health and Lifestyle Questionnaire" by Ruth C. ANOVA and descriptive statistics were employed, with a significance level set at 0.05. The ANOVA analysis revealed a trend toward significance (p = 0.076) in the differences among these cities, emphasizing the complex interplay of factors shaping health and lifestyle. This calls for further exploration of socio-cultural, economic, healthcare, and environmental influences to develop targeted strategies for healthier lifestyles and well-being in these urban areas. In summary, our comprehensive study of lifestyle and health in four Indian cities, each involving 100 subjects, concludes that these cities exhibit notable consistency in both lifestyle choices and health indicators. The lack of statistically significant differences underscores shared patterns of well-being, emphasizing the need for tailored health interventions addressing common challenges and shared strengths. Further research should delve into the factors behind this uniformity and potential nuanced variations. This study underscores the importance of empirical exploration in understanding human behaviour and well-being, offering valuable insights for policymakers, healthcare professionals, and researchers striving to enhance the quality of life in these diverse urban areas.